About This Lesson
In a class activity (“Pin the Blood Type on the Red Blood Cell” Game), students play the role of the enzyme encoded by each allele of the ABO blood type gene to see how a protein encoded by a gene can produce a trait (phenotype). They will see how the combination of proteins encoded by the ABO alleles from each parent can interact to produce the child’s blood type and understand why blood type O is recessive and blood types A and B are dominant. Instructions for preparing inexpensive game manipulatives, and student handout and worksheet are included.